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IRRAflow active irrigation and drainage system: A glimpse into the future of cerebrospinal fluid shunts

Year: 2025

Type: article

Abstract: Chronic hydrocephalus after subarachnoid hemorrhage may become inevitable, necessitating a permanent cerebrospinal fluid shunt. We report a 40-year-old woman with SAH and a CHESS score of 6. We implemented the IRRAflow active irrigation and drainage system which expedited hemorrhage clearance in 4 days compared to one or two weeks longer with standard external ventricular drains. This system reduced the inflammatory load and preserved the arachnoid granulations, which are responsible for CSF resorption. Further, expedited recanalization of the fourth ventricle prevented an exponential increase in intracranial pressure. Collectively, these factors prevented CSF shunt dependency.

Source: Brain Hemorrhages

DOI: 10.1016/j.hest.2025.10.002

Authors: Saif D. Salman, Rabih G. Tawk, Krishnan Ravindran, Daniel A. Tonetti, Nicholas Brandmeir, Behnam Rezai Jahromi, Babak Jahromi, Richard W. Byrne, William D. Freeman

Institutions: Mayo Clinic in Florida, Mayo Clinic, Cooper University Hospital, West Virginia University, Northwestern University, University of Helsinki

Language: English

Topic: Cerebrospinal fluid and hydrocephalus

Subfield: Cellular and Molecular Neuroscience

Field: Neuroscience

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4415901250

FWCI: 0.689

Cites: 16

Cited by: 2

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