Work

Genetic Origins and Clonal Trajectories of Monosomy 7 in Pediatric Mds

Year: 2025

Type: article

Abstract: Conclusions: Early MC analysis in PB combined with monocyte and T cell lineage chimerism monitoring may help predict JMML relapse in a subset of patients.Prospective studies with serial sampling are underway to validate MC kinetics and improve relapse prediction strategies.

Source: EJC Paediatric Oncology

DOI: 10.1016/j.ejcped.2025.100348

Authors: Sushree Sahoo, Victor P. Pastor, Mark van Roosmalen, Dirk Lebrecht, Senthilkumar Ramamoorthy, Charnise Goodings Harris, Anaïs van Leeuwen, Lili Kotmayer, Kristen Schratz, Ayami Yoshimi, Brigitte Strahm, Peter Noellke, Axel Gebert, Ruben van Boxtel, Charlotte M. Niemeyer, Miriam Erlacher, Marcin W. Wlodarski

Institutions: St. Jude Children's Research Hospital, Oncode Institute, Princess Máxima Center, University of Freiburg, Johns Hopkins University, Johns Hopkins Medicine, University Hospital Ulm

Language: English

Topic: Acute Myeloid Leukemia Research

Subfield: Hematology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,340

OpenAlex ID: W4415903455

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