Work

Increasing Antimicrobial Resistance Profile Diversity of Colonizing Group B Streptococcus in Reproductive-Aged Women in Korea

Year: 2025

Type: article

Abstract: Background: (GBS) colonization in pregnant women with a parallel rise in neonatal and infant infections, were observed in Korea. We characterized antimicrobial resistance (AMR) and molecular features of GBS isolates from reproductive-aged women between 1994-2000 and 2017-2022. Methods: genotypes by serotypes, and AMR genes were identified using whole-genome sequencing on the NovaSeq 6000 system (Illumina, San Diego, CA, USA). Results: The number of resistance profiles increased from six to 16, including 11 newly identified patterns, covering 81.8% of levofloxacin resistant isolates. Conclusions: The acquisition of diverse resistance genes has expanded AMR profiles in colonized GBS, emphasizing the need for sustained nationwide surveillance.

Source: Annals of Laboratory Medicine

DOI: 10.3343/alm.2025.0439

Authors: Kwangjin Ahn, Seong Jin Choi, Hye Gyung Bae, Hyukmin Lee, Jong Rak Choi, Young Uh, Yangsoon Lee, Kyungwon Lee

Institutions: Yonsei University, Yonsei University Mirae Campus, Yonsei University Health System, Hanyang University

Language: English

Topic: Neonatal and Maternal Infections

Subfield: Public Health, Environmental and Occupational Health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4415905407

FWCI:

Cites: 36

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