Work

Comparative study on salivary IL- 8 and LDH among tobacco users without lesions, leukoplakia, oral submucous fibrosis and oral squamous cell carcinoma

Year: 2025

Type: article

Abstract: Oral and oropharyngeal malignancies, OSCC accounts for 95% of cases. Diagnosis and prognosis of OSCC relies upon the tumour staging, an important predictor of survival. Therefore, it is of interest to evaluate the changes in the salivary levels of IL-8 and LDH among Tobacco users without lesions, Individuals with Leukoplakia, Oral submucous fibrosis and OSCC. 40 cases were analysed in this study. We show that salivary IL8 and LDH which can serve as one reliable biomarker in early detection of OSCC and a prognostic indicator for OPMDs.

Source: Bioinformation

DOI: 10.6026/973206300213542

Authors: Srinivasan Venkatesh, Saraswathi Gopal K, Nandhini Ganesan

Institutions: Meenakshi Academy of Higher Education and Research, Meenakshi Ammal Dental College and Hospital

Language: English

Topic: Oral Health Pathology and Treatment

Subfield: Periodontics

Field: Dentistry

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

OpenAlex ID: W4415913874