Work

Use of Topical Herbal Remedy for treatment of Drug-Resistant Cutaneous Leishmaniasis: A Case Report

Year: 2025

Type: article

Abstract: Background: Cutaneous leishmaniasis is a parasitic infectious disease characterized by skin lesions and scarring. Although standard treatments are available, some patients experience treatment failure or exhibit inadequate therapeutic responses, highlighting the need for alternative or adjunctive therapies. Case Report: This report describes the case of a 33-year-old woman with treatment-resistant cutaneous leishmaniasis who failed to respond to conventional therapies. The patient voluntarily opted to use the herbal topical product derived from Commiphora myrrha resin. The product was applied topically to the lesion twice daily. After six weeks of consistent application, the lesion healed completely without recurrence. Conclusion: This case highlights the therapeutic potential of C. myrrha resin, which is known for its antiparasitic properties, as a primary treatment option for Leishmania major-induced cutaneous leishmaniasis and as an adjuvant therapy for L. tropica infections. Further research is warranted to validate its efficacy and explore its mechanisms of action in larger clinical studies.

Source: Majallah-i dānishgāh-i ̒ulum-i pizishkī-i Kirmān.

DOI: 10.34172/jkmu.4127

Authors: Mehdi Shafiei-Bafti, Ali Ghobadi, Mahdiye Mohammadnejad, Iraj Sharifi

Institutions: Iran University of Medical Sciences, Kerman University of Medical Sciences

Language: English

Topic: Research on Leishmaniasis Studies

Subfield: Public Health, Environmental and Occupational Health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4415915900