Work

Longitudinal study of chronic stress effects on epilepsy prevalence

Year: 2025

Type: article

Abstract: The relationship between chronic stress exposure and epilepsy prevalence in adults over a 3-year follow-up period is of interest. Hence, a cohort of 145 stress-exposed individuals and matched controls were assessed using validated stress scales and neurological evaluations. Chronic stress was found to significantly increase the risk of new-onset epilepsy, particularly in those with comorbid anxiety and sleep disorders. Neuroinflammatory and neuroendocrine mechanisms are suggested as mediators. Thus, we show the need for early stress intervention in epilepsy prevention.

Source: Bioinformation

DOI: 10.6026/973206300213617

Authors: Gervais Singh Samra, Saika Nazir, Shanmukha Koppolu, Melanie Mary Francis

Institutions: The Royal Wolverhampton NHS Trust, University of Dhaka, Barts Health NHS Trust

Language: English

Topic: Epilepsy research and treatment

Subfield: Psychiatry and Mental health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

OpenAlex ID: W4415944964