Work

Modifiable Risk Factors for Symptom Burden in Chronic Rhinosinusitis With Nasal Polyps: The Role of Obesity and Sleep Apnoea

Year: 2025

Type: article

Abstract: ABSTRACT Objective To identify sociodemographic and clinical predictors of symptom severity and quality of life (QoL) impairment in patients with chronic rhinosinusitis with nasal polyps (CRSwNP), diagnosed according to the latest EPOS 2020 criteria. Study Design Cross‐sectional analytical study. Setting Tertiary Care Center (University Hospital of Jaén, Spain). Methods A total of 188 patients diagnosed with CRSwNP were evaluated. Symptom severity and QoL were assessed using the Nasal Obstruction Symptom Evaluation (NOSE‐E) and the Sino‐Nasal Outcome Test (SNOT‐22). Multiple linear regression analysis was used to identify predictors of symptom burden. Results Higher body mass index (BMI) and the presence of sleep apnoea were independently associated with increased symptom severity, as measured by both the NOSE‐E (adj. R 2 = 0.224, p = 0.002) and the SNOT‐22 (adj. R 2 = 0.242, p = 0.005). Smoking was associated in the bivariate analysis but was not retained in the multivariate models. Conclusion BMI and sleep apnoea are independent predictors of greater symptom burden and poorer QoL in CRSwNP. These findings highlight the importance of incorporating weight management and sleep apnoea screening into the multidisciplinary management of CRSwNP to improve patient outcomes.

Source: Clinical Otolaryngology

DOI: 10.1111/coa.70058

Authors: Javier Modesto García‐Fernández, María Soledad Sánchez‐Torices, María Pilar Gómez‐Gallego, Miguel Ángel Feliz‐Fernández, María Alharilla Montilla‐Ibáñez, Rafael Lomas‐Vega

Institutions: Universidad de Jaén, Complejo Hospitalario de Jaén

Language: English

Topic: Sinusitis and nasal conditions

Subfield: Otorhinolaryngology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $4,520