Work

Distribution and inter-device agreement of chord mu/alpha lengths and axes between Pentacam HR, Sirius, and IOLMaster 700

Year: 2025

Type: article

Abstract: PURPOSE: To evaluate the distribution and inter-device agreement of chord mu (C-µ) and chord alpha (C-α) lengths and axes across three imaging systems-Pentacam HR, Sirius, and IOLMaster 700-in healthy candidates for refractive surgery. METHODS: This cross-sectional study included 101 healthy right eyes. C-µ and C-α were obtained from Pentacam HR, Sirius, and IOLMaster 700. Agreement was assessed using intraclass correlation coefficients (ICC), circular correlation coefficients (CCC), Bland-Altman plots, and paired t-tests. Subgroup analyses were conducted based on refractive status and myopia severity. RESULTS: C-µ and C-α lengths were significantly greater in hyperopic than myopic eyes (C-µ: +0.11-0.13 mm; C-α: +0.15-0.16 mm; P < 0.001). No associations were found with gender or myopia severity. Inter-device agreement for C-µ length was moderate to good overall (ICC: 0.56-0.73), and best in hyperopic eyes (ICC: 0.79-0.91). For the C-µ axis, CCC values showed good agreement between Pentacam HR and Sirius (CCC = 0.81), and moderate agreement between Sirius-IOLMaster 700 (CCC = 0.70) and Pentacam HR-IOLMaster 700 (CCC = 0.68). C-α measurements (available only for Pentacam HR and IOLMaster 700) showed moderate agreement (ICC = 0.68, CCC = 0.51). CONCLUSION: C-µ and C-α measurements vary significantly across devices, with the poorest agreement consistently observed between Pentacam HR and IOLMaster 700, particularly in myopic eyes. These discrepancies are clinically relevant when planning centration-sensitive procedures such as multifocal intraocular lens implantation or wavefront-guided laser-assisted in situ keratomileusis. Surgeons should account for inter-device variability and consider device-specific measurement biases when planning treatment.

Source: Photodiagnosis and Photodynamic Therapy

DOI: 10.1016/j.pdpdt.2025.105275

Authors: Armin Doostparast, Maryam Ghandhari, Mohammadreza Rastegar, Amir Hossein Khosronejad, Mohammadreza Ghandhari, Alireza Eslampoor

Institutions: Mashhad University of Medical Sciences, Mazandaran University of Medical Sciences

Language: English

Topic: Corneal surgery and disorders

Subfield: Radiology, Nuclear Medicine and Imaging

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,610