Work

Association of a Number of Tumor Foci with Ultrasound Patterns and Reoperation Rate in Well-Differentiated Thyroid Cancer (WDTC)—A Single-Center Analysis

Year: 2025

Type: article

Abstract: BACKGROUND: Suspicious ultrasound patterns are essential for the accurate preoperative assessment of thyroid cancer (TC). The number of tumor foci may serve as an additional parameter, particularly when considered in association with ultrasound patterns and the reoperation rate. METHODS: We conducted a retrospective analysis of 665 well-differentiated TC (WDTC) patients treated between 2008 and 2024. The analysis included preoperative data, ultrasound patterns (hypoechogenicity, microcalcifications, high vascularity, and irregular tumor shape or margins), and histopathological findings regarding the number of tumor foci and reoperation rates, additionally stratified by TNM stage and sex. RESULTS: > 0.05). CONCLUSIONS: Although the number of tumor foci demonstrates an association with ultrasound patterns, the lack of a consistent linear correlation and the absence of an impact on reoperation rates suggest that this parameter may provide limited additional clinical value beyond the general concept of multifocality.

Source: Cancers

DOI: 10.3390/cancers17223595