Work

Functional significance of opioid receptor homomers and heteromers

Year: 2025

Type: article

Abstract: A new structural dynamics analysis provides an explanatory bridge between apparently divergent results in the field of opioid receptor oligomerization and, by extension, in the broader field of class A G protein-coupled receptor oligomerization.

Source: Nature Communications

DOI: 10.1038/s41467-025-64693-4

Authors: Sergi Ferré, Francisco Ciruela, Leonardo Pardo

Institutions: National Institutes of Health, National Institute on Drug Abuse, Institut d'Investigació Biomédica de Bellvitge, Universitat de Barcelona, Universitat Autònoma de Barcelona

Language: English

Topic: Receptor Mechanisms and Signaling

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: gold

Estimated APC paid: $6,990

Funders: Universitat de Barcelona, Universitat Autònoma de Barcelona, National Institutes of Health