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Treatment of breakthrough labor pain with epidural dexmedetomidine: a case series

Year: 2025

Type: article

Abstract: Breakthrough labor pain, defined as the return of pain despite ongoing administration of neuraxial analgesia, poses a significant challenge within the field of obstetric anesthesia. Epidural adjunct medications may be used to enhance neuraxial block density or provide coverage to previously spared regions. Dexmedetomidine, a US Food and Drug Administration-approved selective alpha-2 adrenergic agonist, has gained attention for an off-label use as a labor epidural adjunct medication for labor analgesia. This case series highlights three cases of epidural dexmedetomidine use for breakthrough pain during labor.

Source: Baylor University Medical Center Proceedings

DOI: 10.1080/08998280.2025.2580830

Authors: Abigail Blanton, Zehra Tombul, Robert Beck, Weike Tao, Allison A. Mootz

Institutions: The University of Texas Southwestern Medical Center, Parkland Health & Hospital System

Language: English

Topic: Anesthesia and Pain Management

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W4416004030

FWCI:

Cites: 11

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