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Genetic and Functional Evaluation of the Complement System in De Novo Thrombotic Microangiopathy After Transplantation: A Single‐Center Experience

Year: 2025

Type: article

Abstract: simultaneous liver-kidney transplant; sMAC, soluble membrane attack complex; SPK, simultaneous pancreas kidney transplant; TMA, thrombotic microangiopathy; VUS, variant of unknown significance. Social Media:Single-center 15-patient case series of de novo TMA after abdominal transplant shows VUS detected in 71% with 0% having pathogenic variants; functional and genetic panels

Source: Clinical Transplantation

DOI: 10.1111/ctr.70385

Authors: Adam Bregman, Didier A. Mandelbrot, Neetika Garg

Institution: University of Wisconsin–Madison

Language: English

Topic: Complement system in diseases

Subfield: Immunology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

OpenAlex ID: W4416011193

FWCI:

Cites: 4

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Related to: 10