Year: 2025
Type: article
Abstract: Eumelanin, a naturally occurring pigment derived from the oxidative polymerization of 5,6-dihydroxyindole (DHI) and 5,6-dihydroxyindole-2-carboxylic acid (DHICA), has been extensively studied for its role in human biology and its potential applications in biomedical and sustainable electronic fields. By employing X-band electron paramagnetic resonance spectroscopy, this study focuses on eumelanin with different DHI/DHICA ratios, directly comparing monomeric and polymeric forms. The analysis reveals significant differences in the paramagnetic profiles, with changes in spin dynamics and relaxation times closely linked to the distinct macrostructures formed during polymerization. These findings offer valuable insights into how the molecular architecture of eumelanin influences its paramagnetic environments.
Source: ACS Omega
Language: English
Subfield: Biophysics
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $1,935
Funders: Università degli Studi di Napoli Federico II, Consorzio Interuniversitario Nazionale per la Scienza e Tecnologia dei Materiali, Fundação de Amparo à Pesquisa do Estado de São Paulo, Coordenação de Aperfeiçoamento de Pessoal de Nível Superior, Conselho Nacional de Desenvolvimento Científico e Tecnológico, Financiadora de Estudos e Projetos, Fundação para o Desenvolvimento da UNESP, Universidade Estadual Paulista
OpenAlex ID: W4416014196