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Accelerated cartilage regeneration via chondrocyte metabolic reprogramming using nano-steroid-conjugated mesenchymal stem cells in osteoarthritis

Year: 2025
Type: article
Abstract: MSC-Au-Steroid represents a promising multifactorial therapeutic candidate for OA by targeting both metabolic reprogramming and immune modulation. These findings provide strong evidence that MSC-Au-Steroid acts as a disease-modifying agent, addressing multiple pathological factors and offering superior efficacy compared to current therapies.
Source: Theranostics
DOI: 10.7150/thno.120765
Authors: Jong Yeong Lee, Jun Young Park, In Ah Kwon, Su Hyun Lim, Ki Bum Kim, Jun-Young Park, Youn Joo Kang, Sang-Hyun Kim, Dongwoo Khang, Jin Kyeong Choi
Institutions: Jeonbuk National University, Gachon University, Chungbuk National University, Jeonbuk National University Hospital, Eulji University, Eulji University Nowon Eulji Medical Center, Kyungpook National University
Language: English
Subfield: Rheumatology
Field: Medicine
Open Access status: gold
Estimated APC paid: $1,671
OpenAlex ID: W4416016137
FWCI: 4.499
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Cited by: 7
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