Neural stem cell-loaded biohybrid hydrogel improves cochlear implants by electrode-neural coupling and neural regeneration
Year: 2025
Type: article
Abstract: This NSC-laden conductive hydrogel establishes a self-reinforcing therapeutic paradigm that simultaneously resolves electrode-tissue mismatch through optimized bioelectronic interfacing and reverses neurodegeneration via stem cell-mediated SGN regeneration. The dual-function platform pioneers active neural repair for next-generation neuroprosthetics.
Source: Theranostics
DOI: 10.7150/thno.120515
Authors: Menghui Liao, Xin Zhou, Hao Wei, Yanru Qi, Pan Feng, Xin Gao, Yangnan Hu, Yuyang Qiu, Yusong Wang, Hongbo Yang, Zhonghong Zhang, Zhongze Gu, Renjie Chai
Institutions: Beijing Institute of Technology, Nantong University, Zhuhai People's Hospital, Zhongda Hospital Southeast University, State Key Laboratory of Digital Medical Engineering, Southeast University, Nanjing Drum Tower Hospital, Nanjing University, Fudan University, Obstetrics and Gynecology Hospital of Fudan University, University of Electronic Science and Technology of China, Aerospace Center Hospital, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital
Language: English
Subfield: Cellular and Molecular Neuroscience
Field: Neuroscience
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $1,671
OpenAlex ID: W4416016159