Reactive oxygen species/hypoxia dual-responsive polymers combined with melatonin inhibited PANoptosis of retinal ganglion cells for acute glaucoma treatment
Year: 2025
Type: article
Abstract: This simplified but multifunctional delivery system leveraged the widely available and safe compound melatonin in a highly efficient nanoparticle platform. This system offers potent neuroprotective effects to the retina preventing injury caused by acute glaucoma, and thereby providing a promising clinically translatable strategy for the treatment of glaucoma.
Source: Theranostics
DOI: 10.7150/thno.112836
Authors: Shuhan Meng, Weizhou Fang, Yukun Wu, Zhaohua Xia, Tiansheng Chou, Yang Xia, Lexi Ding, Xuezhi Zhou, Xiaobo Xia
Language: English
Subfield: Ophthalmology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $1,671
OpenAlex ID: W4416016161