Work

Clinical Outcomes of Collagen-Based Nasal Packing in Endoscopic Dacryocystorhinostomy

Year: 2025

Type: article

Abstract: Objectives: Endoscopic dacryocystorhinostomy (Endo DCR) is a standard treatment for nasolacrimal duct obstruction, though outcomes may be compromised by intraoperative bleeding and postoperative inflammation. This study evaluated the clinical efficacy of Novacol Fibrillar ® , a collagen-based absorbable hemostatic agent, in Endo DCR. Methods: A retrospective review was conducted on 357 patients who underwent Endo DCR from January 2018 to September 2024. The Novacol group (n = 168) received Novacol packing, while the Nasopore group (n = 189) received Nasopore. Primary outcomes included anatomical and functional success, operative time, and intraoperative bleeding. Secondary outcomes included granulation, infection, epistaxis, postnasal drip, and revision surgery within 3 months. Results: The Novacol group showed higher anatomical (94.6% vs 85.2%, P = .039) and functional (93.5% vs 84.1%, P = .023) success. Intraoperative bleeding was lower (9.5 vs 12.4 gauzes, P = .022), as were rates of granulation (9.5% vs 24.3%, P = .009), epistaxis (5.4% vs 21.7%, P = .028), postnasal drip (6.5% vs 23.3%, P = .032), and revision surgery (2.4% vs 16.4%, P = .041). Infection rates were not significantly different ( P = .083). Conclusions: Novacol Fibrillar improved surgical outcomes and reduced complications in Endo DCR, supporting its use as an effective hemostatic packing material.

Source: Ear Nose & Throat Journal

DOI: 10.1177/01455613251392335

Authors: Hyunkyu Lee, Sehyun Baek

Institutions: Korea University, Korea University Anam Hospital, Korea University Guro Hospital

Language: English

Topic: Nasolacrimal Duct Obstruction Treatments

Subfield: Ophthalmology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,650