Work

Long-term patient-reported outcomes in pediatric partial-thickness burns using Epiprotect® and Biobrane® a retrospective comparative study

Year: 2025

Type: article

Abstract: Background: Larger pediatric partial-thickness (PT) burns are typically managed with debridement and a skin substitute. Epiprotect® has shown comparable acute surgical outcomes and lower infection rates than Biobrane®, but data on long-term outcomes remain limited. Purpose: To compare long-term patient-reported outcomes between Biobrane® and Epiprotect® in pediatric PT burns using the Brisbane Burn Scar Impact Profile (BBSIP). Methods: We included all pediatric patients (<18 years) treated with Biobrane® or Epiprotect® for PT burns at our center between February 2018 and July 2023 who completed the BBSIP survey >12 months after injury. Total BBSIP scores were analyzed using Wilcoxon rank-sum tests and a negative binomial regression, adjusting for total body surface area (TBSA) and burn depth. Results: = 0.006). Conclusions: Epiprotect® was associated with improved long-term outcomes compared to Biobrane®, particularly in larger or deeper burns. These findings support its use when long-term function and well-being are prioritized.

Source: JPRAS Open

DOI: 10.1016/j.jpra.2025.11.002