Work

Diffusion Models for conditional MRI generation

Year: 2025
Type: preprint
Abstract: In this article, we present a Latent Diffusion Model (LDM) for the generation of brain Magnetic Resonance Imaging (MRI), conditioning its generation based on pathology (Healthy, Glioblastoma, Sclerosis, Dementia) and acquisition modality (T1w, T1ce, T2w, Flair, PD). To evaluate the quality of the generated images, the Fréchet Inception Distance (FID) and Multi-Scale Structural Similarity Index (MS-SSIM) metrics were employed. The results indicate that the model generates images with a distribution similar to real ones, maintaining a balance between visual fidelity and diversity. Additionally, the model demonstrates extrapolation capability, enabling the generation of configurations that were not present in the training data. The results validate the potential of the model to increase in the number of samples in clinical datasets, balancing underrepresented classes, and evaluating AI models in medicine, contributing to the development of diagnostic tools in radiology without compromising patient privacy.
Authors: del Castillo, Miguel Herencia García, Garcia, Ricardo Moya, Mazón, Manuel Jesús Cerezo, Garcia, Ekaitz Arriola, Fernández-Miranda, Pablo Menéndez
Language: English
Open Access status: green
OpenAlex ID: W4416042822
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