Work

ABNO‐Catalyzed Oxidative Dehydrogenation of N ‐Heterocycles in the Synthesis of N ‐Heteroarenes

Year: 2025

Type: article

Abstract: ABSTRACT We report a method for catalyzing the oxidative dehydrogenation of tetrahydroquinoline and indoline derivatives under metal‐free conditions. With 9‐azabicyclo[3.3.1]nonane N ‐oxyl (ABNO) as the catalyst in the presence of potassium tert‐butoxide ( t BuOK), this approach facilitates the efficient oxidative dehydrogenation of partially saturated N ‐heterocyclic arylamines to their aromatic counterparts, offering an alternative approach for N ‐heterocycle synthesis.

Source: Asian Journal of Organic Chemistry

DOI: 10.1002/ajoc.70256

Authors: Hongtao Yang, Hui Han, Limin Wang, Hao‐Yang Wang, Jianwei Han

Institutions: East China University of Science and Technology, Chinese Academy of Sciences, Shanghai Institute of Organic Chemistry

Language: English

Topic: Oxidative Organic Chemistry Reactions

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: bronze

Funder: National Natural Science Foundation of China

Award: G5693488821