Microvascular Dysfunction Assessed by 82Rb PET/CT as a Diagnostic Tool of Chronic Active Myocarditis
Year: 2025
Type: article
Study design: Case Report
Abstract: Immune-related myocarditis may be challenging. We report the case of a 66-year-old man with a history of treated multiple myeloma by using immune checkpoint blockers, referred for angina. Coronary angiography was normal. [ 82 Rb]Rubidium PET/CT found diffuse abnormal stress myocardial blood flow and reserve and the apparition of epicardial calcifications. [ 68 Ga]Ga-DOTATOC PET/CT and CMR revealed chronic calcified myocarditis, which was confirmed by histology. This case emphasizes microvascular dysfunction in chronic active myocarditis as assessed by perfusion PET/CT.
Source: Clinical Nuclear Medicine
Institutions: Centre hospitalier universitaire d'Orléans, Laboratoire Interdisciplinaire pour l’Innovation et la Recherche en Santé d’Orléans, Inserm, Université Paris Cité, Assistance Publique – Hôpitaux de Paris, Paris Cardiovascular Research Center, Hôpital Bichat-Claude-Bernard, Laboratoire de Recherche Vasculaire Translationnelle
Language: English
Subfield: Cardiology and Cardiovascular Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W4416070672