Work

Polymeric nanofiber systems for the encapsulation and delivery of biological entities in food, pharmaceutical, and biomedical fields

Year: 2025

Type: article

Abstract: Biological entities encompass all living or once-living components of the natural world, including molecules, cells, and organisms. Recent advancements have demonstrated the potential of incorporating small molecules, living cells, and microorganisms into polymeric nanofibers for biomedical applications. This interdisciplinary method merges nanofibers' distinctive characteristics with living entities' biological functions to tackle issues in regenerative medicine. Methods like electrospinning have successfully incorporated biological components into nanofibrous structures while preserving their viability and activity. These hybrid constructs create a conducive microenvironment that encourages cell growth, proliferation, and differentiation, thus aiding tissue regeneration. Furthermore, this cutting-edge technique is helpful in the food sector and in biocatalytic contexts. This review examines the incorporation of biological entities into polymeric nanofibers and investigates their possible applications.

Source: Reactive and Functional Polymers

DOI: 10.1016/j.reactfunctpolym.2025.106552

Authors: Rajkumar Patel, Pratheep Kumar Annamalai, Ramanujam Brahmadesam Thoopul Srinivasa Raghava, Madhumita Patel

Institutions: University of Nebraska Medical Center, The University of Queensland, University of Southern Queensland, Amrita Vishwa Vidyapeetham

Language: English

Topic: Electrospun Nanofibers in Biomedical Applications

Subfield: Biomaterials

Field: Materials Science

Domain: Physical Sciences

Open Access status: hybrid

Estimated APC paid: $3,920

OpenAlex ID: W4416091843

FWCI: 0.939

Cites: 117

Cited by: 5

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