Work

Neutrophil to lymphocyte ratio varies in magnitude and biomarker utility based on patient demographics

Year: 2025

Type: article

Abstract: Ang et al. show that a widely studied biomarker for immunotherapy varies based on patient demographics, and that it may only predict outcomes in certain populations.

Source: Journal of Clinical Investigation

DOI: 10.1172/jci198948

Authors: William Ang, Travis D. Kerr, Ananya Kodiboyena, Cristina Valero, Joris L. Vos, Vladimir Makarov, Alex A. Adjei, Luc G.T. Morris, Stephanie L. Schmit, Natalie L. Silver, Sujata Patil, Daniel J. McGrail

Institutions: Cleveland Clinic, Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Memorial Sloan Kettering Cancer Center

Language: English

Topic: Inflammatory Biomarkers in Disease Prognosis

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $5,200

Funders: American Cancer Society, National Institutes of Health, National Cancer Institute

Awards: G7413706836, Cancer Center Support Grant, Variation in tumor-associated immune profiles and colorectal cancer outcomes, Molecular mediators of disparate outcomes experienced by patients of African ancestry with lung cancer

OpenAlex ID: W4416112183

FWCI: 0.723

Cites:

Cited by: 2

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