Clinical effect of non-convulsive electroconvulsive therapy combined with olanzapine in patients with schizophrenia
Year: 2025
Type: article
Study design: Clinical Trial
Abstract: Objective: To explore the clinical effect of non-convulsive electroconvulsive therapy combined with olanzapine in schizophrenia patients. Methods: From September 2021 to August 2023, a total of 112 patients with schizophrenia treated in our hospital were selected as the study participants. These patients were randomly divided into a control group and a research group, with 56 cases in each group. Patients in the control group were administered olanzapine tablets. Based on olanzapine tablets, patients in the research group received non-convulsive electroconvulsive therapy. The psychotic symptoms, severity of schizophrenia symptoms, memory ability, cognitive function, serum BDNF, S100B, and GFAP levels, and incidence of adverse reactions between the two groups were compared. Results: > 0.05). Conclusion: Non-convulsive electroconvulsive therapy combined with olanzapine has a significant effect in the treatment of schizophrenia. It can effectively improve mental symptoms and cognitive function of patients, regulate the levels of serum BDNF and S100B, and has high safety.
Source: Frontiers in Neurology
Authors: Kecai Tao, Qian Xiong, Jinghua Wu
Institutions: Sichuan University, Dongguan People’s Hospital
Language: English
Subfield: Psychiatry and Mental health
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $3,801
OpenAlex ID: W4416126378