A Review of Analytical Techniques for the Analysis of Oral Smokeless Products and Heated Tobacco Products
Year: 2025
Type: article
Abstract: The increasing popularity in recent years of oral smokeless products (OSPs) and heated tobacco products (HTPs) has raised significant public health and regulatory concerns. Although these products are often marketed as less harmful alternatives to traditional cigarettes, they differ considerably in both design and, more importantly, in their chemical composition. Notably, they contain potentially dangerous compounds such as tobacco-specific nitrosamines, flavorings, heavy metals, and nicotine, which can be addictive and harmful to human health at certain concentrations. This work provides an overview of the analytical techniques and methods used to analyze OSPs and HTPs, including the determination of moisture content and pH, the extraction of various compounds, the generation of HTP aerosol, and non-targeted analysis, as well as the quantification of extracted compounds using gas chromatography, liquid chromatography, and spectroscopy. Identifying and quantifying the chemical composition of OSPs and HTPs is essential for assessing their health impact and developing proper regulatory standards regarding these products.
Authors: Matjaž Rantaša, David Majer, Matjaž Finšgar
Institution: University of Maribor
Language: English
Subfield: Physiology
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
Awards: The development of a highly sensitive electrochemical method for trace determination of antibiotic compounds based on magnetic polymeric nanocomposites in environmental systems, Process systems engineering and sustainable development, G2820714014, Textile Chemistry and Advanced Textile Materials, Comparative study on the potential of biofuels industry effluents utilization for the production of biopolymer of microbial origin, Development of electrochemical gas sensor for early detection of volatile peroxo explosives
OpenAlex ID: W4416128751