Work

Low-valent cobalt catalyzed direct dehydroxylative cross-coupling of benzyl alcohols with aryl-chlorides

Year: 2025

Type: article

Abstract: ) cross-coupling reaction between benzyl alcohols and a broad range of aryl chlorides. The success of this transformation is attributed to the development of low-coordinate cobalt/bipyridine complexes, which enable the selective conversion of benzyl alcohols into the corresponding diarylmethanes, while minimizing undesired homocoupling of either the benzyl alcohol or aryl chlorides.

Source: Chemical Science

DOI: 10.1039/d5sc05919d

Authors: Prashant S. Shinde, Valmik S. Shinde, Magnus Rueping

Institutions: King Abdullah University of Science and Technology, Central Drug Research Institute

Language: English

Topic: Catalytic Cross-Coupling Reactions

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: diamond

Funder: King Abdullah University of Science and Technology

Awards: G4038520284, G5034435374