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Zinc Phosphide Poisoning in Pregnancy: A Rare Case Report From Nepal

Year: 2025
Type: article
Study design: Case Report
Abstract: ABSTRACT Zinc phosphide (Zn 3 P 2 ) poisoning during pregnancy is exceedingly unusual and potentially lethal, with no previously known occurrences globally. We present a 26‐year‐old woman, gravida 2 para 1, at 29 weeks gestation, who took 15 g of Zn 3 P 2 in a suicidal attempt and experienced non‐projectile vomiting. Her vital signs were stable (BP 110/80 mmHg, GCS 15/15), but she experienced transitory hepatic dysfunction that improved on Day 4 with supportive therapy such as coconut oil gastric lavage, intravenous fluids, and pantoprazole. The fetal scan confirmed viability (heart rate of 158 bpm). The high mortality of Zn 3 P 2 (37%–100%) is caused by phosphine gas‐induced suppression of mitochondrial respiration. This case emphasizes the lack of a particular antidote and the significance of immediate decontamination, hepatic monitoring, and mental follow‐up following purposeful consumption.
Language: English
Field: Medicine
Open Access status: gold
Estimated APC paid: $1,820
OpenAlex ID: W4416143259
FWCI:
Cites: 8
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