Work

Garlicinals A–D: Bioactive Organosulfur α,β-Unsaturated Aldehydes from Garlic ( Allium sativum L.) Hydrolate

Year: 2025

Type: article

Abstract: High Resolution Image Download MS PowerPoint Slide Four sulfur-derived compounds, garlicinals A–D ( 1–4 ), were isolated from the garlic ( Allium sativum ) bulb hydrolate. The structural elucidation of 1–4 was achieved with the help of HRMS and 1D and 2D NMR. All of these compounds are characterized by an α,β-unsaturated aldehyde in their structure. Noteworthy, this structural motif is unique in garlic-derived compounds, which would convert them into a new family of garlic-derived organosulfur compounds. A synthetic path to these compounds is proposed. Garlicinals A–C showed potent fungicidal activity against plant pathogens ( Aspergillus niger and Botrytis cinerea ). Furthermore, 1–4 were active against the nematode Meloidogyne javanica .

Source: ACS Omega

DOI: 10.1021/acsomega.5c09432

Authors: Alberto Galisteo, José F. Quílez del Moral, Alejandro F. Barrero, María F Andrés, Azucena Gonzalez-Coloma

Institutions: Universidad de Huelva, Universidad de Granada, Consejo Superior de Investigaciones Científicas, Instituto de Ciencias Agrarias, Institute of Agricultural Sciences

Language: English

Topic: Garlic and Onion Studies

Subfield: Plant Science

Field: Agricultural and Biological Sciences

Domain: Life Sciences

SDG: Zero hunger

Open Access status: gold

Estimated APC paid: $1,935