Work

Adalimumab as a Potential Therapeutic Option for Metastatic Crohn's Disease With Genital Lesions and Edema: A Case Report

Year: 2025

Type: article

Abstract: Metastatic Crohn's disease (MCD) is a rare and complex extraintestinal manifestation of Crohn's disease (CD) that often profoundly affects patients' quality of life. This report presents a meticulously detailed case of a 12-year-old Iranian girl with persistent labial swelling and genital lesions, later diagnosed as MCD. The case highlights the diagnostic challenges and successful treatment with adalimumab. The study sheds light on the diagnostic intricacies, therapeutic dilemmas, and limited treatment options associated with MCD, a rare condition. This case study advances our understanding of MCD treatment and paves the way for exploring the promising efficacy of adalimumab in managing this challenging condition.

Source: Clinical Case Reports

DOI: 10.1002/ccr3.71424

Authors: Hoda Haghshenas, Behnaz Darban, Mohammad Aref Bagherzadeh, Mehdi Karimi, Maryam Ataollahi

Institutions: Jahrom University of Medical Sciences, Hormozgan University of Medical Sciences, Bogomolets National Medical University, Shiraz University of Medical Sciences

Language: English

Topic: Inflammatory Bowel Disease

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,820