Work

Paediatric bladder melanosis: a rare case report

Year: 2025

Type: article

Abstract: Bladder melanosis is a rare, typically benign histological finding involving melanin pigment deposition in the urothelium without melanocytes. Fewer than 40 reported cases exist, with only one prior paediatric case report. We present a 13-year-old male with a history of posterior urethral valves and ongoing bladder dysfunction. Cystoscopy showed brown bladder pigmentation and biopsy confirmed bladder melanosis with melanin pigment and chronic inflammation but no atypia or malignancy. Follow-up showed resolution with no specific treatment required. This is only the second reported paediatric case and highlights the importance of histological evaluation to confirm diagnosis and exclude malignancy.

Source: Urology Case Reports

DOI: 10.1016/j.eucr.2025.103266

Authors: Suzannah Woodhouse, Alexander Cho, Athanasios Tyraskis, Sharmila Sanchez, Thivya Sekar

Institution: Great Ormond Street Hospital

Language: English

Topic: Urinary and Genital Oncology Studies

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,160