Work

Complete spontaneous resolution of NRAS -mosaic multiple congenital melanocytic naevi: proof of principle for therapeutic mole reversal

Year: 2025

Type: article

Abstract: We present a unique case of complete spontaneous resolution of multiple congenital melanocytic naevi (CMN) with 18 years of photographic, histological and genetic evidence. This case is of biological importance as proof of principle that CMN are not permanent malformations, but instead potentially reversible lesions. In turn, this proof of principle is of clinical importance, as the increased risk of melanoma development would be expected to disappear with the naevi.

Source: British Journal of Dermatology

DOI: 10.1093/bjd/ljaf447

Authors: Daniela Dyankova-Peeva, Veronica A Kinsler

Institutions: Great Ormond Street Hospital, University College London, The Francis Crick Institute

Language: English

Topic: Cutaneous Melanoma Detection and Management

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $4,920