Work

Design, Synthesis, and Anti-inflammatory Activity Evaluation for Hydrazide-Based HDAC6 Targeted Protein Degraders

Year: 2025

Type: article

Source: Journal of Medicinal Chemistry

DOI: 10.1021/acs.jmedchem.5c02554

Authors: Simin Sun, Kairui Yue, Enqiang Liu, Danmei Sheng, Yuxin Chen, Tianqi Li, Aijun Shen, Geng Jia, Yuqi Jiang, Xiaoyang Li

Institutions: National Medical Products Administration, Qilu Hospital of Shandong University, Ocean University of China, Marine Biomedical Research Institute of Qingdao

Language: English

Topic: Protein Degradation and Inhibitors

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: Ocean University of China, Natural Science Foundation of Shandong Province, Qingdao Municipal Science and Technology Bureau, National Key Research and Development Program of China

Awards: G7209871012, G8694491198, G887477577

OpenAlex ID: W4416168591

FWCI: 0.761

Cites: 58

Cited by: 3

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