Work

AC/DC: Highway to cell

Year: 2025

Type: article

Abstract: Apoptotic cell (AC) corpses can be taken up by certain types of dendritic cell (DC), which cross-present dead cell-derived antigens. In this issue of JEM, Tam et al. (https://doi.org/10.1084/jem.20250887) reveal that GPR34, a lysophosphatidylserine receptor, promotes AC uptake and cross-presentation by type 1 DCs (cDC1s).

Source: The Journal of Experimental Medicine

DOI: 10.1084/jem.20251958

Authors: Victor Bosteels, William Stainier, Caetano Reis e Sousa

Institution: The Francis Crick Institute

Language: English

Topic: Immunotherapy and Immune Responses

Subfield: Immunology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

OpenAlex ID: W4416187277