Work

Double trouble: A novel case report of synchronous bilateral renal cell carcinoma of differing histology

Year: 2025

Type: article

Abstract: Renal cell carcinomas account for 2-3 % of all malignancies. In non-familial syndrome patients, another kidney tumor synchronous, antecedent, or subsequent to diagnosis of RCC is relatively rare. It is very rare for the kidney tumor to be malignant and of differing pathology altogether. We herein describe a 67-year old male with bilateral synchronous masses treated with open bilateral adrenal sparing radical nephrectomy. His final pathology was interestingly found to have novel, differing aggressive cancers: a TFE3-rearranged RCC and a grade 4 WHO clear cell RCC.

Source: Urology Case Reports

DOI: 10.1016/j.eucr.2025.103274

Authors: Andrew Shanholtzer, Sahith Kaki, Shane Daugherty, Dongping Shi, Mazen Abdelhady

Institutions: Detroit Medical Center, Lake Erie College of Osteopathic Medicine

Language: English

Topic: Renal cell carcinoma treatment

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,160