Work

NHANES data are irrelevant for ketogenic diet research – Comment on “Ketogenic diets are associated with an elevated risk of hypertension: Insights from a cross-sectional analysis of the NHANES 2007–2018″

Year: 2025

Type: article

Abstract: In a recent study titled "Ketogenic diets are associated with an elevated risk of hypertension: Insights from a cross-sectional analysis of the NHANES 2007-2018", Qu et al. have used data from the NHANES, a large survey of American citizens, to correlate the participants' dietary ketogenic ratio (DKR) to hypertension. They find a significant positive correlation and conclude, as the title of their article suggests, that ketogenic diets (KDs) are associated to hypertension risk. However, their basic assumption that the participants' DKR has anything to do with a KD constitutes a serious mistake, as I argue in this Commentary. The reason is that even the highest quartile of DKR corresponds to a non-ketogenic diet. In conclusion, the data utilized by Qu et al. are irrelevant to their research question and cannot be used to support the hypothesis that KDs increase the risk of hypertension.

Source: International Journal of Cardiology Cardiovascular Risk and Prevention

DOI: 10.1016/j.ijcrp.2025.200534

Author: Rainer J. Klement

Institutions: Leopoldina Krankenhaus Schweinfurt, Universitätsklinikum Würzburg

Language: English

Topic: Diet and metabolism studies

Subfield: Physiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,710