Year: 2025
Type: article
Abstract: NoCut safeguards genome integrity against persistent DNA bridges, but how these missegregation events are sensed is not understood. In this issue, Dam et al. (https://doi.org/10.1083/jcb.202502014) identify the Srs2 and PARI helicases as conserved NoCut sensors that initiate signalling to delay cytokinetic abscission.
Source: The Journal of Cell Biology
Author: Juan Martin-Serrano
Institution: King's College London
Language: English
Topic: DNA Repair Mechanisms
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: bronze
OpenAlex ID: W4416202235