Cardiomyopathy Associated with Subclinical Becker Muscular Dystrophy in a Patient Presenting with Anesthesia-induced Rhabdomyolysis
Year: 2025
Type: article
Study design: Case Report
Abstract: Becker muscular dystrophy (BMD)-associated cardiomyopathy may be overlooked in patients with dilated cardiomyopathy (DCM). We herein report a case of cardiomyopathy related to BMD in which anesthesia-induced rhabdomyolysis led to a diagnosis of BMD. The patient experienced anesthesia-induced rhabdomyolysis during cardiac resynchronization therapy. The patient became inotrope-dependent, and a left ventricular assist device was safely implanted by considering the use of anesthetic agents to avoid rhabdomyolysis. The abnormal immunohistochemical staining pattern of dystrophin protein in the myocardium and dystrophin gene mutation confirmed the diagnosis of BMD. BMD should thus be considered in patients with DCM to prevent perioperative complications including rhabdomyolysis.
Source: Internal Medicine
Authors: Kento Kumai, Hiroki Mochizuki, Takuya Watanabe, Keiko Ohta-Ogo, Taisuke Ishikawa, Makoto Araki, Chisato Ota, Katsuki Nagatomo, Gaku Narita, Hirotaka Kawauchi, Reiko Shiomura, Terufumi Iwanaga, Takuma Sato, Osamu Seguchi, Yoshihiko Ikeda, Kinta Hatakeyama, Naomasa Makita, Satsuki Fukushima, Yasumasa Tsukamoto
Language: English
Subfield: Cardiology and Cardiovascular Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4416202408