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Why is your separase such a big protease?

Year: 2025

Type: article

Abstract: Recent structural work explains a fundamental event during cell division, the timely and specific cleavage of the chromosomal cohesin complex by the protease separase.

Source: Science Advances

DOI: 10.1126/sciadv.aec7431

Authors: Céline Bouchoux, Frank Uhlmann

Institution: The Francis Crick Institute

Language: English

Topic: Microtubule and mitosis dynamics

Subfield: Cell Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: gold

Estimated APC paid: $4,500

OpenAlex ID: W4416203193

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Cites: 11

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