Neuronal differentiation and tissue engineering strategies for central nervous system injury repair
Year: 2025
Type: article
Abstract: Central nervous system (CNS) injury can cause devastating neurological dysfunction in patients, permanently impairing their ability to take care of themselves and reducing their quality of life. At present, neural tissue engineering is the most promising way to treat this disease. However, there are still many challenges and obstacles in the process of correctly structuring tissue engineering. The successful development of tissue engineering relies on three key components: biological scaffold materials, seed cells, and various growth factors. In summary, this review provides a systematic analysis of scaffold materials differentiation strategies for inducing diverse stem cells into neuro‐like cells. The synthesized findings not only accelerate regenerative medicine approaches but also provide the critical solutions for CNS injury treatment and advance therapeutic development, offering important references for future research and clinical translation.
Source: BMEMat
DOI: 10.1002/bmm2.70044
Authors: Zhuqing Xia, Jinghui Zhang, Na Ren, Shuping Wang, Congcong Zhang, Nik Ahmad Nizam Nik Malek, Wan Hairul Anuar Kamaruddin, Chao Liu, Chunhui Sun, Jingang Wang
Language: English
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4416204856