Intravascular lithotripsy for the treatment of calcified coronary artery disease: A case series
Year: 2025
Type: article
Abstract: Objectives: Severe coronary artery calcification poses major challenges to percutaneous coronary intervention, often limiting stent expansion and procedural success. The Sonico-CX intravascular lithotripsy (IVL) system is a novel calcium-modification device designed to fracture calcified plaques using acoustic shockwaves. Methods: We present a case series of 21 patients with balloon-undilatable, severely calcified lesions treated with this new IVL system. All procedures were performed by experienced interventional cardiologists between April and August 2024. Adjunctive noncompliant and scoring balloons were used, and 4 cases required rotational atherectomy to facilitate IVL delivery. Results: IVL achieved a high procedural success rate (90.5%) with no intraprocedural complications or inhospital and 30-day major adverse cardiovascular events. The use of IVL enabled effective drug-coated balloon therapy in 85.7% of cases, reducing the need for stent implantation. Conclusions: This case series highlights the safety and efficacy of a novel IVL system and its potential to simplify complex percutaneous coronary intervention by providing effective lesion preparation in heavily calcified coronary disease.
Source: Asian Heart Journal
Authors: Julian Wei Ee Tong, En Tze Chan, BuiKiong Chung, HweiSung Ling, How Kiat Khor, AndyTze Yang Ko, Kit Hou Chiang, Lai Kuan Leong, Ing Xiang Pang, ChengFoong Cheah, Esteban Yu Hern Chin, Francis Eng Pbeng Shu, Chen Ting Tan, Keng Tat Koh, Yen Yee Oon, Yee Ling Cham, Said Asri, Alan Yean Yip Fong, Tiong Kiam Ong
Institution: Universiti Malaysia Sarawak
Language: English
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4416205117