Work

2-Oxoindolin-thiazoline hybrids as scaffold-based therapeutics for T2DM-associated cognitive impairment: design, synthesis, in vitro and in silico studies

Year: 2025

Type: article

Abstract: ADME profiling indicated desirable pharmacokinetic properties, further supporting the therapeutic potential of these compounds as dual-action agents for the management of Alzheimer's disease and type 2 diabetes mellitus.

Source: RSC Medicinal Chemistry

DOI: 10.1039/d5md00628g

Authors: Wesam S. Qayed, Mostafa A. Hassan, Halil Şenol, Parham Taslimi, Tarek Aboul-Fadl

Institutions: Assiut University, Bezmiâlem Vakıf Üniversitesi, Bartin University

Language: English

Topic: Synthesis and biological activity

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W4416210350

FWCI: 1.162

Cites: 35

Cited by: 4

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