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Slaying the Serpent: Pearls and Pitfalls of Crotalid Envenomations

Year: 2025

Type: article

Abstract: Crotalid envenomations pose a significant clinical challenge for emergency medicine physicians, largely due to the potential for severe local toxicity, extensive tissue damage, and even systemic toxicity. This case report reviews the clinical presentation and anti-venom management of a patient who presented to our local emergency department after sustaining a crotalid envenomation to the left hand. Our case highlights common pitfalls in emergency management, including the non-interchangeability of dosing for available North American antivenoms. We briefly discuss the comparative efficacy of the two available North American antivenoms, CroFab® (BTG International, Inc., West Conshohocken, PA) and Anavip® (Rare Disease Therapeutics, Inc., Poway, CA).

Source: Cureus

DOI: 10.7759/cureus.96847

Authors: Nikolas P Foresteire, Tyler Kellett, Krishen Gosine, Kelly Grabbe, Anthony Jackson, Cory Howard

Institutions: University of South Florida, HCA Healthcare

Language: English

Topic: Venomous Animal Envenomation and Studies

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: diamond

Funder: HCA Healthcare