Work

Primary squamous cell carcinoma of the endometrium: A case report

Year: 2025

Type: article

Abstract: RATIONALE: Primary squamous cell carcinoma of the endometrium (PSCCE) has a low incidence and is relatively rare. The treatment for this disease is currently not well-defined. Here, we report a case of a 56-year-old female patient. Based on a review of previous literature, we summarized the treatment options for this rare disease and presented our insights. PATIENT CONCERNS: A 55-year-old patient presented with postmenopausal vaginal bleeding. Transvaginal ultrasonography demonstrated uterine cavity hydrocele and abnormal echo. Diagnostic hysteroscopy was performed, and pathological results revealed PSCCE. DIAGNOSIS: The patient was diagnosed with primary squamous cell carcinoma of the endometrium (stage IA). INTERVENTIONS: The patient underwent laparoscopic total hysterectomy and bilateral adnexectomy, combined with pelvic and para-aortic lymph node dissection. Then she received external beam radiotherapy and brachytherapy. OUTCOMES: The patient has been undergoing regular follow-up and so far, no recurrence of the tumor has been detected. LESSONS: Primary squamous cell carcinoma of the endometrium is rare, no definitive treatment protocol has been established. Early diagnosis is important for prognosis.

Source: Medicine

DOI: 10.1097/md.0000000000045920

Authors: Shuhui Cui, Zhe Dong

Institution: Peking University International Hospital

Language: English

Topic: Endometrial and Cervical Cancer Treatments

Subfield: Obstetrics and Gynecology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,950