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Diagnostic challenges in bleeding renal tumors: A ruptured papillary renal cell carcinoma showing regression followed by progression

Year: 2025

Type: article

Abstract: A man in his 60s with a history of a right renal tumor presented with right abdominal pain. Imaging revealed tumor rupture with retroperitoneal hemorrhage. Although initial conservative treatment led to temporary tumor shrinkage, significant regrowth occurred over the next 4 years, necessitating radical nephrectomy. The pathological diagnosis was papillary renal cell carcinoma (PRCC). This case highlights the intrinsic fragility of PRCC-a type of renal cancer prone to spontaneous bleeding. It also highlights the importance of considering renal cell carcinoma in the differential diagnosis of renal hemorrhage, not just angiomyolipoma. Notably, PRCC can rupture even with subtle imaging findings. Crucially, this case emphasizes the need for strict and long-term follow-up in conservatively managed ruptured renal tumors because apparent regression does not guarantee complete resolution.

Source: Radiology Case Reports

DOI: 10.1016/j.radcr.2025.10.051