Work

Unraveling metabolic complexity of multi-payload PEG-irinotecan prodrug: A deconvolution-based LC-Q-TOF MS approach for preclinical pharmacokinetic characterization

Year: 2025

Type: article

Source: Chinese Chemical Letters

DOI: 10.1016/j.cclet.2025.112099

Authors: Shiwen Song, Mingyang Zhao, Xiangrong Song, Huaidong Yu, Xin Xu, Dong Sun, Jingkai Gu

Institutions: Hainan University, Sichuan University, West China Hospital of Sichuan University, State Key Laboratory of Biotherapy, Jilin University, State Key Laboratory of Supramolecular Structure and Materials

Language: English

Topic: Metabolomics and Mass Spectrometry Studies

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: National Natural Science Foundation of China, Natural Science Foundation of Hainan Province

Awards: G4362772121, G5554167322, G7968040600, G8686921669

OpenAlex ID: W4416229981

FWCI: 0.24

Cites: 18

Cited by: 1

Related to: 10