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Cutaneous manifestations of injection drug use

Year: 2025
Type: article
Abstract: The opioid crisis in the United States has led to a significant increase in the number of people who inject drugs (PWID) in the last 20 years. PWID have high risk of morbidity and mortality, and they experience diverse and severe cutaneous diseases. Injection drug use involves a series of steps and exposures. Each step puts a person at risk for injury and infection with cutaneous manifestations. In order for dermatologists to appropriately diagnose and treat PWID, they must understand the process of injection drug use and associated harm reduction strategies. PWID can present with cutaneous diseases including skin and soft tissue infections; systemic bacterial, fungal, and viral infections; vascular complications; injuries; pruritus and formication; and allergic disease. Drug adulterants, including levamisole and xylazine, can cause characteristic cutaneous findings. Appropriate diagnosis and management of cutaneous disease by dermatologists is a critical part of caring for PWID.
Language: English
Subfield: Epidemiology
Field: Medicine
Open Access status: gold
Estimated APC paid: $2,000
OpenAlex ID: W4416230576
FWCI: 0.623
Cites: 47
Cited by: 1
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