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Supplemental Figure 2 from MTA-Cooperative PRMT5 Inhibitors Are Efficacious in MTAP-Deleted Malignant Peripheral Nerve Sheath Tumor Models

Year: 2025

Type: supplementary-materials

Abstract: Supplemental Figure 2. The SAM-cooperative PRMT5 inhibitor GSK3326595 is not selective for MTAP status in MPNST cell lines.

DOI: 10.1158/1078-0432.30617724

Authors: Xiaochun Zhang, Dana C. Borcherding, Minjie Zhang, Yang Lyu, Guangfeng Wang, Kevin He, Gorkem Oztosun, Ishita Sachdeva, Liuzhan Yang, Kuangying Yang, Alex Yuen, Heather DiBenedetto, Alice Tsai, Alan Huang, John P. Maxwell, Kevin M. Cottrell, Kimberly J. Briggs, Angela C. Hirbe

Language: English

Topic: Cancer-related gene regulation

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4416232107

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