Work

CYP2C19 Genotype Is Not Associated With the Risk of Microscopic Colitis

Year: 2022

Type: article

Abstract: Microscopic colitis (MC) is a cause of chronic diarrhea, defined by grossly normal appearing mucosa with lymphocytic invasion or collagen deposition on histology.1 The pathophysiology of MC remains unclear. Medications from diverse classes, including proton pump inhibitors (PPIs), selective serotonin reuptake inhibitors (SSRIs), histamine 2 receptor antagonists (H2RAs), 3-hydroxy-3-methyl-glutaryl-CoA (HMG-CoA) reductase inhibitors, and nonsteroidal anti-inflammatory drugs (NSAIDs), have been described as potential causes of MC.

Source: Gastro Hep Advances

DOI: 10.1016/j.gastha.2022.09.013

Authors: K.C. Darlington, A.F. Peery, T.O. Keku, J.T. Woosley, R.S. Sandler

Institution: University of North Carolina at Chapel Hill

Language: English

Topic: Microscopic Colitis

Subfield: Gastroenterology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,000