Work

Discovery of Potent, Allosteric GSTO1 Covalent Inhibitors with a New Binding Mode

Year: 2025

Type: article

Source: Journal of Medicinal Chemistry

DOI: 10.1021/acs.jmedchem.5c01724

Authors: Yanli Sun, Fengying Zhang, Lixin Zhou, Yixuan Feng, Shuke Yang, Qiuxian Lu, Xin Yuan, Wenqing Hou, Biwei Liu, Zhixiang Guo, Lu Chen, Bo Peng, Xianzhen Yin, Yiwen Zhang, Jing Yang, Nan Chen, Wenchao Lu

Institutions: ShanghaiTech University, Nanjing Health and Health Commission, Tongji University, Sichuan University, West China Hospital of Sichuan University, State Key Laboratory of Biotherapy, Anhui Medical University, First Affiliated Hospital of Anhui Medical University

Language: English

Topic: Inflammasome and immune disorders

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

Funder: Science and Technology Commission of Shanghai Municipality

Award: G347621492

OpenAlex ID: W4416239383

FWCI: 1.305

Cites: 24

Cited by: 5

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