Work

PHIP sequences and dipolar fields II—Dual-channel control

Year: 2026

Type: article

Abstract: Parahydrogen induced polarisation (PHIP) achieves efficient hyperpolarisation of nuclear spins at room temperature with the transfer of the singlet order of parahydrogen to target molecules through catalytic hydrogenation reactions and subsequent coherent control of the spin dynamics. However, in realistic conditions B0/B1 inhomogeneities, imperfect chemical equivalence and dipolar fields arising from the magnetisation of the sample can degrade polarisation transfer efficiency significantly. In this work (part II), we extend the theoretical framework of part I (Korzeczek et al., 2026) to dual-channel sequences which drive both the carbon-13 (/heteronuclear) and hydrogen spins. This allows for strong robustness properties at increased transfer rates and an increased robustness to chemical shifts between the parahydrogen spins.

Source: Journal of Magnetic Resonance

DOI: 10.1016/j.jmr.2026.108091

Authors: Martin C. Korzeczek, Ilai Schwartz, Martin B. Plenio

Institutions: Universität Ulm, Center for Integrated Quantum Science and Technology

Language: English

Topic: Advanced NMR Techniques and Applications

Subfield: Spectroscopy

Field: Chemistry

Domain: Physical Sciences

Open Access status: hybrid

Estimated APC paid: $3,500